Origins and Applications of CRISPR-Mediated Genome Editing

John R. Christin, Michael V. Beckert

Abstract


In this graphical review we highlight key milestones in the discovery and development of CRISPR and cas9 technology, as well as illustrate mechanisms of cas9:sgRNA target binding and DNA repair.

Keywords


CRISPR; genome editing; CRISPR history; CAS9

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DOI: http://dx.doi.org/10.23861/EJBM201631754

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